Similac Sensitive vs Total Comfort Comparison Guide

Similac Sensitive vs Total Comfort

Similac Sensitive vs Total Comfort Comparision Guide- Similac Sensitive and Similac Total Comfort are two popular and widely consumed baby formulas in the United States. Both these formulas are formulated and sold by Abbott Nutrition- a big tycoon in the baby formula industry, under the brand name Similac. 

Abbott Nutrition claims that both these high-quality infant formulas are light and easy on babies’ tummies and they do not result in digestive problems in babies. This is one significant similarity between Similac Sensitive and Similac Total Comfort Formula. However, there are more similarities and differences between them that make it difficult for parents to decide which formula to choose for their babies. 

Since you are here on this page, we will not disappoint you. We have prepared a comprehensive Similac Sensitive vs Total Comfort comparison guide that will help you make the right decision on choosing a Similac Baby Formula for your baby. We have put together the important details of both Similac Baby Formulas, including their ingredients, benefits, and suitability for different baby needs.

Overviewing Similac Sensitive (Similac Sensitive vs Total Comfort)

Before coming to the Similac Sensitive vs Similac Total Comfort comparison part, let’s first overview both these products. 

Similac Sensitive is a specifically formulated baby formula that caters to babies who have sensitive digestive systems and experience difficulties in digesting lactose. This formula is carefully made to provide complete nutrition while at the same time being gentle on delicate digestive systems. Here’s what you need to know more about Similac Sensitive:

Lactose Intolerance

Lactose Intolerance or sensitivity is one of the main reasons parents choose Similac Sensitive. Babies with lactose sensitivity can more easily digest this formula because it is a lactose-free formula. It’s a great option for infants who get gassy, bloated, or fussy after eating.

Complete Nutrition

Similac Sensitive doesn’t skimp on vital nutrients despite being created for sensitive stomachs. It offers a well-balanced mixture of the proteins, lipids, vitamins, and minerals required for the growth and development of your infant.

Important Features 

  • The easily digestible gentle carbohydrates avoid fussiness that takes place due to lactose sensitivity
  • OptiGRO- a special blend that comprises DHA for brain and eye development, Lutine for healthy eyes, and Vitamin E for developing cells. 
  • Prebiotics for supporting and making strong the digestive system
  • Some amount of calcium excluding palm olein oil to support bones growth 
  • Carotenoids that are naturally found in breast milk
  • Nucleotides to strengthening the immune system
  • A blend of carbohydrates to support maximizing absorption and minimize malabsorption
  • Low osmolality, Halal, and Kosher
  • Gluten-free formula

Find the complete nutrition data for Similac Sensitive formula below.

Complete Nutrition Data

Safety & Precaution For Similac Sensitive Formula 

  • This formula is strictly not for infants with galactosemia 
  • Do not warm the formula using a microwave as it may result in serious burns
  • The powder form of Similac Sensitive formula is not sterile and you should not feed it to your baby if he/she is premature or has immune problems
  • Do not let the formula to expose to chemical compounds as this may result in severe problem
  • Do not add additions to the formula until recommended by the pediatrician 

At Which Store You Can Buy Similac Sensitive? 

You can buy Similac Sensitive both online and offline store. The popular online store options are Amazon, Target, and Walmart. You can also purchase the formula from the official Similac website and some other online portals. 

In case, you want to buy Similac Sensitive from an offline store, this Similac Sensitive vs Similac Total Comfort Comparison Guide recommends you use Abbott Nutrition’s Store Locator feature for that. You will surely find a reliable store near your location. 

This PDF is sourced from Abbott Nutrition. We do not hold any rights to the content, pictures, and illustrations shown in this pdf.

Overviewing Similac Total Comfort (Similac Sensitive vs Similac Total Comfort)

Similac Sensitive vs Total Comfort Comparison Guide– Another popular option for parents looking for a formula that encourages simple digestion and reduces discomfort is Similac Total Comfort. To solve feeding difficulties, this formula contains almost everything that you may find in the Similac Sensitive Baby formula. However, it adopts a different strategy which includes:

Gentle Protein Source

Protein that has been partially hydrolyzed or broken down into smaller protein molecules is the highlight of Similac Total Comfort. The partially hydrolyzed protein makes digestion completely easy and comfortable for babies who have difficulty breaking down whole proteins.

Reduced Allergy Risk

Similac Total Comfort’s hydrolyzed protein lessens the possibility of causing allergies. This makes it a good choice if your family has a history of allergies or if your infant is more likely to get allergies than the average child.

Prebiotics Promote Gut Health

Prebiotics in this formula encourages the development of healthy bacteria in your baby’s gastrointestinal tract. The immune system and overall digestive health are supported by a healthy gut flora.

These are the main highlight of the Similac Total Comfort. The features, preparation methods, and precautions are almost the same for Similac Total Comfort as for Similac Sensitive. 

This PDF is sourced from Abbott Nutrition. We do not hold any rights to the content, pictures, and illustrations shown in this pdf.

Similac Sensitive vs Total Comfort: Differences

Now that you have an overview of both products, let’s dive into the Similac Sensitive vs Total Comfort actual comparison. Here is the comparison:

Sugar Levels

Similac Sensitive: A balanced amount of sugar is present in this formula. It is made to be mild on delicate tummies, give your baby energy, and boost growth.

Similac Total Comfort: Similar to Similac, Similac Total Comfort also contains sugars, but due to the inclusion of partially hydrolyzed protein, it may have a variable carbohydrate composition.


Similac Sensitive: Lactose isn’t found in the Similac Sensitive formula. Its formulation makes it suitable for infants who might be lactose intolerant.

Similac Total Comfort: This formula’s partially hydrolyzed protein may result in lower lactose content, making it a possibility for infants with delicate gastrointestinal systems.

Presence Of 2′-FL HMO

Similac Sensitive: This formula often doesn’t have HMOs such as 2′-FL (2′-fucosyllactose), which are found in human milk.

Similac Total Comfort: Some formulations of Similac Total Comfort are enhanced with 2′-FL HMO, which can aid in the development of a healthy gut and immune system, while not all versions of the product may have HMOs.

Digestion Technique

Similac Sensitive: To suit sensitive tummies, Similac Sensitive’s digesting strategy focuses on a reduction in lactose and mild proteins. This is the major difference that you can find in Similac Sensitive vs Similac Total Comfort. 

Similac Total Comfort: Protein that has been partially hydrolyzed, or broken down into smaller pieces, is used in the formula’s digesting process. Babies with gastrointestinal allergies may find it simpler to process thanks to this.


Similac Sensitive: Similac Sensitive still offers vital nutrients, including proteins, lipids, vitamins, and minerals, despite being designed for sensitive stomachs. It seeks to provide whole nourishment while attending to digestive issues.

Similac Total Comfort: This formula’s combination of partially hydrolyzed protein, lipids, and other necessary components is intended to give well-rounded nourishment.

Considerations for Allergens

Similac Sensitive: Although this formula is made to be mild on delicate stomachs, it is not specifically made for infants with severe allergies or sensitivities.

Similac Total Comfort: While comparing Similac Sensitive vs Total Comfort, it comes to know that hydrolyzed proteins have less allergenic potential than intact proteins. And this is why they may be suitable for infants who are at risk of allergies.

Intended Use

Similac Sensitive: Similac Sensitive is primarily designed for infants who exhibit mild digestive sensitivity symptoms including gas, bloating, or fussiness.

Similac Total Comfort: Due to its partially hydrolyzed protein, this formula is excellent for infants who have a history of allergies or severe digestive distress.

These are the Similac Total Comfort vs Sensitive differences that you must keep in mind before purchasing one. 

What Formula Should You Give Your Baby?

You Depending on your baby’s particular needs and sensitivities, you should choose between Similac Sensitive and Similac Total Comfort. This Similac Sensitive vs Similac Total Comfort comparison guide may have assisted you in understanding which could be a better pick for you. However, here are a few things to think about before choosing one between these:

Digestion Issue 

Both formulas can provide comfort if your baby develops gas, colic, or fussiness after feeding. However, babies with severe digestion problems can benefit particularly from the hydrolyzed protein in Similac Total Comfort.

Lactose Intolerance

Similac Sensitive is designed to address lactose intolerance if it is a problem. It provides a lower lactose level without sacrificing important nutrients.

Risk of Allergy

Similac Total Comfort’s hydrolyzed protein can be a wise choice to reduce the risk of inducing allergies if there is a family history of them or you think your baby might be susceptible to them.

Gut Wellness

The prebiotic ingredient of Similac Total Comfort can help newborns with gut-related pain have better digestive systems.

Why Can’t You Purchase a Similac Baby Formula For Your Baby Randomly? 

Every infant takes birth with unique abilities. It heavily depends on the genes that parents pass. And possibly, because of that, some babies are lactose intolerant while there are many that are sensitive to certain ingredients found in baby formulas. This is the major reason you can’t randomly pick a Similac Baby Formula type and start feeding that to your baby. 

A certified and highly-qualified pediatrician can assist you better in comparing Similac Sensitive vs Total Comfort and deciding which one of these is a perfect match for your baby’s dietary needs. 

What Problems Your Baby Can Face When Feeding Him/Her A Wrong Baby Formula?

Babies and soft and super sensitive. Anything that is hard on their tummies can result in severe problems. They may cause digestion and gas problems in your baby and because of this, your baby may experience severe pain in their tummies. 

Apart from this, your baby is prone to diarrhea, bloating, wheezing, coughing, vomiting, and swelling as well. Some other problems that your baby may develop if consume the wrong baby formula include

Allergic Reactions: Your little one may be allergic or sensitive to certain ingredients found in Similac Sensitive or Similac Total Comfort Formula. If you pick the wrong formula out of these two, it may trigger allergic reactions in your baby resulting in rashes, hives, or even anaphylaxis. Thus, it is crucial to conduct a Similac Sensitive vs Total Comfort comparison before picking one out of these. 

Improper Growth and Development of Your Baby: Different Similac baby formulas are formulated to mimic breast milk and meet the different needs of babies. The nutrients, vitamins, and minerals found in these formulas are present in different quantities and concentrations. Using the wrong Similac baby formula can result in nutritional imbalances which are deficiencies or excesses of certain nutrients. This can lead to improper growth and development of your cutest baby. 

Cognitive and Neural Development: Most Similac baby formulas include fatty acids like DHA (docosahexaenoic acid). This ingredient is included in the formula, particularly for healthy brain and neural development. The right balance of this ingredient leads to proper cognitive and neural development but if you use the wrong formula, you may serve an imbalanced DHA diet to your baby which might affect cognitive development in the long run.

Colic and Fussiness: Babies may turn excessively irritable, fussy, and colicky if you feed them the wrong formula. And because of this, you may have to visit your nearest pediatrician multiple times. To avoid these issues and discomforts in your babies, it is advised to do proper research and analysis on Similac Sensitive vs Total Comfort. Also, do not forget to consult with your pediatrician. 

Growth Delays and Weight Issues: Every parent wish the healthy growth and development of their babies. For this, it is crucial for you to provide appropriate and adequate nutrients to him/her. If you are unable to do that or you pick the wrong baby formula for your baby, it may lead to growth delays and poor weight gain. 

Gastroesophageal Reflux (GERD): Gastroesophageal reflux refers to a condition where stomach contents flow back into the esophagus. Some babies might be prone to this and if you feed them the wrong baby formula, it can only exacerbate this condition.

Risk of Bacterial Infections: Bacterial infection risk is always there with milk-based products like Similac. It doesn’t heavily depend on the type of formula you buy for your baby but on how you handle and store the formula. However, if you purchase an expired or spoiled baby formula, you may face a bacterial infection issue.

So, to avoid bacterial infection, make sure you do not buy expired or spoiled baby formula. And also, make sure you deal with the baby formula as instructed. A careless approach in storing and handling the baby formula can spoil the entire formula. 

Final Thoughts on Similac Sensitive vs Total Comfort

Similac Sensitive and Similac Total Comfort were both carefully engineered to address typical eating issues. The individual demands and sensitivities of your infant will determine your decision. Before altering your baby’s feeding schedule or picking any of these two, always consider this Similac Sensitive vs Similac Total Comfort comparison guide and also check with your pediatrician.

Ultimately, choosing wisely between these two formulas will guarantee that your baby’s nutritional requirements are covered while reducing discomfort and encouraging healthy growth.

FAQs For Similac Sensitive vs Similac Total Comfort

What's the difference between Similac Sensitive vs Total Comfort?

The main difference lies in the approach to addressing digestive issues. Similac Sensitive is formulated to address lactose sensitivity, while Similac Total Comfort focuses on reducing discomfort caused by gas and fussiness.

Can both Similac Sensitive and Total Comfort formulas be used for babies with lactose sensitivity?

Similac Sensitive is specifically designed to address lactose sensitivity, making it a better choice for babies with this concern. Similac Total Comfort, on the other hand, is designed to be gentler on the baby’s digestive system in general.

Which formula is better for babies with gas and fussiness issues out of Similac Total Comfort vs Sensitive?

Similac Total Comfort is formulated to reduce gas and fussiness, making it a potential choice for babies experiencing these issues. Its partially hydrolyzed protein can be easier for some babies to digest.

Can I switch between these formulas if my baby is having digestive issues?

It’s always best to consult with your pediatrician before making any formula changes. They can provide guidance on whether a switch is necessary and which formula might be more suitable based on your baby’s specific needs.

Are these formulas hypoallergenic?

While neither formula is labeled as hypoallergenic, Similac Total Comfort may be suitable for babies with mild sensitivities since it uses partially hydrolyzed protein.

Do these formulas require a prescription?

These formulas are generally available over-the-counter and do not typically require a prescription. However, if your pediatrician recommends a specific formula due to your baby’s unique needs, they might provide a prescription.

Can I mix these formulas with breast milk?

Yes, you can mix these formulas with breast milk if desired. Consult with your pediatrician to determine the appropriate mixing ratio based on your baby’s needs.

How do I know which formula is best for my baby?

Comparing Similac Sensitive vs Similac Total Comfort can give you an idea of which formula could be better for your baby. However, your pediatrician is the best person to guide you in selecting the right formula for your baby. They can consider your baby’s specific needs and any existing sensitivities to recommend the most suitable option.

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